ScenTree, la nouvelle encyclopédie des ingrédients de parfum.

Exploring the branches of scent

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Crédits photo: ScenTree SAS

CAS number :

1506-02-1

EINECS number :

216-133-4

FEMA number :

Data not available.

JECFA number :

Data not available.

FLAVIS number :

Data not available.

Volatility :

Base

Appearance :

White solid

Price Range :

€€

Stability :

Musks are very stable, as in alcoholic and in functional fragrances

Density :

1.005

Molecular formula :

C₁₈H₂₆O

Molecular Weight :

258.4 g/mol

Flash Point :

>212°F (>100°C)

Log P :

Data not available.

Fusion Point :

131°F (55°C)

Boiling Point :

Data not available.

Detection Threshold :

Data not available.

Crédits photo: ScenTree SAS

Year of discovery :

Discovered in 1954.

Synthesis route :

Tonalide® is a polycyclic musk, synthesized from 1,1,2,4,4,7-hexamethyltetralin. This compound is synthesized by a reaction between alpha-para-dimethylstyrene and tetramethylethene, in an acid medium. It can also be prepared by a Friedel-Crafts reaction between para-Cymene and 3,3-dimethyl-1-butene in the presence of aluminium chloride. The last synthesis step is an acetylation with chloroacetic acid in the presence of aluminium chloride.

Synthesis precursor :

Tonalide® is not a precursor to the synthesis of another compound of olfactory interest.

Isomerism :

Galaxolide® is another musk and a constitutional isomer of Tonalide®, with a quite similar smell.

Natural availability :

Tonalide® is not available in its natural state.

Allergens :

This ingredient does not contain any allergen.

For more information on allergens used in perfumery, please consult our article about allergens

IFRA :

This ingredient is not restricted

Maximum usage according to the product category :
Ingredients containing
Ingredient Name	CAS N°	Estimated Concentration

Skin contact products	Non skin contact products
Leave on products	Rinse off products

List of natural ingredients containing the material presented here
Ingredient Name	Botanical Name	CAS N°	Estimated Concentration

Maximum usage according to the product category :
Ingredients containing
Ingredient Name	CAS N°	Estimated Concentration

List of natural ingredients containing the material presented here
Ingredient Name	Botanical Name	CAS N°	Estimated Concentration

To learn more about IFRA's standards : https://ifrafragrance.org/safe-use/library
To find out the specificities of each category and the ingredients prohibited by IFRA, click article about l'IFRA
ScenTree is solely responsible for the information provided here.

Uses in perfumery :

Tonalide® is used in men's fragrances, in combination with other musks. Good fixator and substantivity.
Used in all types of fragrances, especially in body care. Its earthy note can stand out if this raw material is overdosed.

Other names :

Ganolide®, Tetralide®, 1-(3,5,5,6,8,8-hexamethyl-6,7-dihydronaphthalen-2-yl)ethanone, acetyl hexamethyl tetralin, 6-acetyl-1,1,2,4,4,7-hexamethyl tetralin, AHMT, fixolide, muscofix, musk tetralin, 1-(5,6,7,8- tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one

Other comments :

Tonalide® has a very similar smell to Galaxolide®. It is one of the most expensive musk. Like some other polycyclic musks,Tonalide® is not biodegradable and causes major pollution problems. As a result, some companies have decided to ban this compound from their products.

Cat.1	Cat.2	Cat.3	Cat.4	Cat.5A	Cat.5B	Cat.5C	Cat.5D	Cat.6

Cat.7A	Cat.7B	Cat.8	Cat.9	Cat.10A	Cat.10B	Cat.11A	Cat.11B	Cat.12

Exploring the branches of scent

Year of discovery :

Discovered in 1954.

Synthesis route :

Synthesis precursor :

Tonalide® is not a precursor to the synthesis of another compound of olfactory interest.

Isomerism :

Galaxolide® is another musk and a constitutional isomer of Tonalide®, with a quite similar smell.

Natural availability :

Tonalide® is not available in its natural state.

Allergens :

This ingredient does not contain any allergen.

Annexe I :

Restriction type :

Cause of restriction :

Amendment :

Comments :

Quantitative usage limits :

Annexe I :

Annexe I :

Restriction type :

Cause of restriction :

Amendment :

Comments :

Quantitative limit on the use :

Annexe I :